Hemochromatosis (HFE) (N-Term) Peptide
HFE
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977959
Quick Overview for Hemochromatosis (HFE) (N-Term) Peptide (ABIN977959)
Target
HFE
(Hemochromatosis (HFE))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MGASEQDLGL SLFEALGYVD DQLFVFYDHE SRRVEPRTPW VSSRISSQMW
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HFE Antibody(ARP44283_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HFE (Hemochromatosis (HFE))
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Background
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HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
Alias Symbols: HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2
Protein Interaction Partner: B2M,TFR2,TFRC,TFR2,TFRC
Protein Size: 348 -
Molecular Weight
- 40 kDa
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Gene ID
- 3077
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NCBI Accession
- NM_000410, NP_000401
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UniProt
- Q30201
Target
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